Heart Attack Damage To Heart Muscle Reduced With New Drug
Heart attack is a scary phrase and rightfully so. According to the Centers for Disease Control and Prevention (CDC), around 5.7 million adults in the United States have heart failure.
The overall statistics are abysmal and alarming:
People with heart failure struggle with everyday activities. They feel weak, tire easily, and have trouble breathing. Other symptoms include weight gain and swelling in the feet, ankles, legs, and stomach.
Heart Attack: New Drug To The Rescue?
The drug blocks the protein MAP4K4, MAP4K4 kills heart muscle cells and damages and scars the heart tissues.
Currently there are no therapies that prevent muscle cell death of the heart. MAP4K4 is the first drug that shows promise.
Heart Attack: Testing MAP4K4 on Human Heart Cells
The researchers used chemicals to induce stress in heart cells and human heart muscle tissue that they had grown from human induced stem cells.
Results showed how stress activated the heart cell killer MAP4K4 protein. Blocking the protein, on the other hand, protected the heart cells from stress-induced death.